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Besides its interest for diagnosis, the finding of an elevated serum AMH level in PCOS has open major pathophysiological issues. This review addresses the three most important issues: 1- the… Click to show full abstract
Besides its interest for diagnosis, the finding of an elevated serum AMH level in PCOS has open major pathophysiological issues. This review addresses the three most important issues: 1- the role of AMH in the disturbed folliculogenesis of PCOS; 2- the role of AMH in the gonadotropin dysregulation of PCOS and 3- the role of AMH in the trans-generational transmission of PCOS. For each of those issues, the clinical and experimental evidences currently available are discussed and pathophysiological hypothesis are proposed.
Keywords:
anti llerian;
hormone pathogenesis;
role anti;
llerian hormone;
role;
role amh
Journal Title: Frontiers in Endocrinology
Year Published: 2020
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Journal Title: Frontiers in Endocrinology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!