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Galectins play relevant roles in tumor development, progression and metastasis. Accordingly, galectins are certainly enticing targets for medical intervention in cancer. To date, however, clinical trials based on galectin inhibitors… Click to show full abstract
Galectins play relevant roles in tumor development, progression and metastasis. Accordingly, galectins are certainly enticing targets for medical intervention in cancer. To date, however, clinical trials based on galectin inhibitors reported inconclusive results. This review summarizes the galectin inhibitors currently being evaluated and discusses some of the biological challenges that need to be addressed to improve these strategies for the benefit of cancer patients.
Keywords:
biological challenges;
challenges clinical;
cancer biological;
galectins cancer;
inhibition galectins;
cancer
Journal Title: Frontiers in Immunology
Year Published: 2023
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Journal Title: Frontiers in Immunology
Year Published: 2023
Link to full text (if available)
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recommendations!