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An Intelligent Diagnostic System for Thyroid-Associated Ophthalmopathy Based on Facial Images

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Background Thyroid-associated ophthalmopathy (TAO) is one of the most common orbital diseases that seriously threatens visual function and significantly affects patients’ appearances, rendering them unable to work. This study established… Click to show full abstract

Background Thyroid-associated ophthalmopathy (TAO) is one of the most common orbital diseases that seriously threatens visual function and significantly affects patients’ appearances, rendering them unable to work. This study established an intelligent diagnostic system for TAO based on facial images. Methods Patient images and data were obtained from medical records of patients with TAO who visited Shanghai Changzheng Hospital from 2013 to 2018. Eyelid retraction, ocular dyskinesia, conjunctival congestion, and other signs were noted on the images. Patients were classified according to the types, stages, and grades of TAO based on the diagnostic criteria. The diagnostic system consisted of multiple task-specific models. Results The intelligent diagnostic system accurately diagnosed TAO in three stages. The built-in models pre-processed the facial images and diagnosed multiple TAO signs, with average areas under the receiver operating characteristic curves exceeding 0.85 (F1 score >0.80). Conclusion The intelligent diagnostic system introduced in this study accurately identified several common signs of TAO.

Keywords: system; facial images; associated ophthalmopathy; thyroid associated; intelligent diagnostic; diagnostic system

Journal Title: Frontiers in Medicine
Year Published: 2022

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