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Wall-free droplet microfluidics for probing biological processes by high-brilliance X-ray scattering techniques

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Here we review probing biological processes initiated by the deposition of droplets on surfaces by micro- and nanobeam X-ray scattering techniques using synchrotron radiation and X-ray free-electron laser sources. We… Click to show full abstract

Here we review probing biological processes initiated by the deposition of droplets on surfaces by micro- and nanobeam X-ray scattering techniques using synchrotron radiation and X-ray free-electron laser sources. We review probing droplet evaporation on superhydrophobic surfaces and reactions with substrates, basics of droplets deposition and flow simulations, droplet deposition techniques and practical experience at a synchrotron beamline. Selected applications with biological relevance will be reviewed and perspectives for the latest generation of high-brilliance X-ray sources discussed.

Keywords: high brilliance; biological processes; scattering techniques; ray scattering; ray; probing biological

Journal Title: Frontiers in Molecular Biosciences
Year Published: 2022

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