LAUSR

Activity of neurons embedded in networks is an inseparable composition of intrinsic and evoked processes. Prevalence of either component depends on the neuron’s function (e.g., signal pacemaker vs. transmitter) and state (e.g., low vs. high depolarization states). Complex firing patterns of a neuron are conventionally attributed to complex spatial-temporal organization of inputs received from the network-mates via synapses, in vast majority dendritic. However, these views require revisiting with account of active properties of the dendrites. Structural features of the arborization inevitably impact on electrical states of its constituting parts at different levels of organization, from branches and sub-trees to ion channels. This Research Topic aimed at bringing together contributions of researches from different domains and gaining deeper insight into the nature of neuronal intrinsic firing patterns. Being cross-listed in Frontiers in Cellular Neuroscience and Frontiers in Computational Neuroscience, it contains 22 articles (14 and 8 in the respective journal specialties, respectively) including 14 original research articles, 4 reviews; 1 mini review, 1 methods, and 2 hypothesis and theory articles.