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Evasion from apoptosis is a hallmark of cancer. Inhibitor of apoptosis proteins (IAPs) contribute to this hallmark by suppressing the induction of cell death. IAPs were found to be overexpressed… Click to show full abstract
Evasion from apoptosis is a hallmark of cancer. Inhibitor of apoptosis proteins (IAPs) contribute to this hallmark by suppressing the induction of cell death. IAPs were found to be overexpressed in cancerous tissues and to contribute to therapeutic resistance. The present review focuses on the IAP members cIAP1, cIAP2, XIAP, Survivin and Livin and their importance as potential therapeutic targets in bladder cancer.
Keywords:
inhibitor apoptosis;
apoptosis;
targets bladder;
apoptosis proteins;
cancer;
therapeutic targets
Journal Title: Frontiers in Oncology
Year Published: 2023
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Journal Title: Frontiers in Oncology
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!