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Effect of tumor microenvironment on ferroptosis: inhibition or promotion

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Ferroptosis is a type of lipid peroxidation-induced, iron-dependent programmed cell death. Emerging evidence suggests that ferroptosis is intimately connected to tumorigenesis, development, treatment and plays a major role in tumor… Click to show full abstract

Ferroptosis is a type of lipid peroxidation-induced, iron-dependent programmed cell death. Emerging evidence suggests that ferroptosis is intimately connected to tumorigenesis, development, treatment and plays a major role in tumor immune regulation. This study focused on the connection between ferroptosis and immune regulation, which may offer a theoretical basis for targeting ferroptosis and tumor immunotherapy.

Keywords: effect tumor; microenvironment ferroptosis; tumor microenvironment; ferroptosis inhibition; tumor; ferroptosis

Journal Title: Frontiers in Oncology
Year Published: 2023

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