LAUSR

The discovery and development of a biologically active molecule with therapeutic properties is an increasingly complex task, highly unpredictable at the early stages and frequently marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very long and costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (a small molecule or a macromolecule of natural or synthetic origin) with those targets, and to facilitate the study of the pharmacokinetics, pharmacodynamics and toxicity of an active agent in both suitable models and human subjects.