LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

The inhibitory effect of some pyrazole ligands and their Cu(II) complexes on the growth of Escherichia coli, Klebsiella–Enterobacter spp., and Staphylococcus aureus

Photo by jeremybishop from unsplash

The aim of this study was to evaluate the inhibitory activity of chemistry products against the growth of Escherichia coli, Klebsiella–Enterobacter spp., and Staphylococcus aureus. Pyrazole derivatives (4-bromo-2-(1H-pyrazol-3-yl)phenol, 4-nitro-3-pyrazolecarboxylic acid,… Click to show full abstract

The aim of this study was to evaluate the inhibitory activity of chemistry products against the growth of Escherichia coli, Klebsiella–Enterobacter spp., and Staphylococcus aureus. Pyrazole derivatives (4-bromo-2-(1H-pyrazol-3-yl)phenol, 4-nitro-3-pyrazolecarboxylic acid, N-(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine), 3-amino-5-hydroxypyrazole, 3,5-pyrazoledicarboxylic acid monohydrate, and selected complexes of Cu(II) with the mentioned pyrazoles as ligands were used as chemistry bioactives for antibacterial activity. The testing method was carried out according to the disc diffusion method. Some compounds have shown inhibitory effects against the growth of E. coli. A small number of compounds have shown inhibitory effects against the growth of Klebsiella–Enterobacter spp. but did not show inhibitory effects on Staphylococcus aureus compared to amoxicillin as a standard.

Keywords: klebsiella enterobacter; growth; enterobacter spp; chemistry; staphylococcus aureus; growth escherichia

Journal Title: Frontiers in Pharmacology
Year Published: 2022

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.