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Improving Non-specific Immunity to Coronavirus Disease (COVID-19) by the Novelty, Diversity, and Quantity of Antigen

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The health crisis caused by the COVID-19 pandemic continues to claim thousands of lives around the world. The current challenge for the scientific community, along with governments, is to quickly… Click to show full abstract

The health crisis caused by the COVID-19 pandemic continues to claim thousands of lives around the world. The current challenge for the scientific community, along with governments, is to quickly find solutions to save lives and limit the consequences of the crisis. The scientific community is currently tackling the problem primarily by aiming to develop a vaccine to enable the body to develop an antigen-specific immune response to COVID-19. This approach requires time-consuming studies in order to understand the underlying properties of COVID-19 and to deploy the vaccine (1), which is very challenging to achieve at pandemic speed (2). Moreover, it could be compromised by mutations in the COVID-19 genome (3). However, it is essential to note that the problem could be approached from at least one other front for more rapid deployment in a pandemic context. Too little consideration has been devoted to the roles of the non-specific immune response via natural killer (NK) cells, which continue to be neglected in research into vaccines (4).

Keywords: non specific; covid; immunity coronavirus; improving non; antigen; specific immunity

Journal Title: Frontiers in Public Health
Year Published: 2020

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