LAUSR

This study investigated the effects of transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (dlPFC) at three intensities (sham, 1 mA, 2 mA) on postural control, isokinetic strength, and cognitive performance in women with fibromyalgia (FM) and healthy controls (HCs). Using a double-blind, sham-controlled, crossover design, 26 participants (13 FM, 13 HC) completed sessions in randomized order, performing tasks under single- and dual-task conditions. Cognitive accuracy improved in both groups following 1 mA and 2 mA stimulation, particularly during single-task scenarios in static balance tasks. Notably, 2 mA tDCS reduced dual-task cost (DTC) in cognitive performance for the FM group, indicating decreased cognitive–motor interference. However, postural and strength outcomes showed no consistent intensity-dependent changes, with only selected nonlinear centers of pressure metrics (e.g., Lyapunov exponent, DFA) indicating possible modulation in FM. Isokinetic strength measures remained largely unaffected by tDCS across all intensities. Overall, the findings suggest that dlPFC-tDCS may selectively enhance cognitive function and reduce cognitive–motor interference in FM, especially under low-demand or higher-intensity stimulation conditions, while offering limited benefits for physical strength and balance.