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How Human Single-Neuron Recordings Can Help Us Understand Cognition: Insights from Memory Studies

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Understanding human cognition is a key goal of contemporary neuroscience. Due to the complexity of the human brain, animal studies and noninvasive techniques, however valuable, are incapable of providing us… Click to show full abstract

Understanding human cognition is a key goal of contemporary neuroscience. Due to the complexity of the human brain, animal studies and noninvasive techniques, however valuable, are incapable of providing us with a full understanding of human cognition. In the light of existing cognitive theories, we describe findings obtained thanks to human single-neuron recordings, including the discovery of concept cells and novelty-dependent cells, or activity patterns behind working memory, such as persistent activity. We propose future directions for studies using human single-neuron recordings and we discuss possible opportunities of investigating pathological brain.

Keywords: human single; single neuron; neuron recordings; memory; cognition

Journal Title: Brain Sciences
Year Published: 2021

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