Simple Summary Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths, and Hispanic/Latino patients are often diagnosed at younger ages and more advanced stages than Non-Hispanic White patients. However,… Click to show full abstract
Simple Summary Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths, and Hispanic/Latino patients are often diagnosed at younger ages and more advanced stages than Non-Hispanic White patients. However, the genetic factors contributing to these differences are not well understood. This study analyzed genetic mutations in key cancer-related pathways to identify differences between these two populations. By examining publicly available data, researchers found that certain mutations in pathways involved in tumor growth and treatment response were more common in Hispanic/Latino patients. These findings provide new insights into the molecular differences in HCC between ethnic groups, which could help improve early detection and develop more effective, personalized treatments. Understanding these differences may also guide future research focused on reducing health disparities and improving outcomes for underrepresented populations.
               
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