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Impact of Preoperative CT-Diagnosed Sarcopenic Obesity on Outcomes After Radical Cystectomy for Bladder Cancer

Simple Summary Sarcopenia has been widely investigated as a predictor of postoperative complications. More recently, increasing attention has been devoted to additional body composition parameters, such as sarcopenic obesity. This… Click to show full abstract

Simple Summary Sarcopenia has been widely investigated as a predictor of postoperative complications. More recently, increasing attention has been devoted to additional body composition parameters, such as sarcopenic obesity. This study contributes to the growing body of evidence supporting the role of body composition assessment in predicting outcomes after radical cystectomy. Our findings emphasize the clinical utility of preoperative computed tomography (CT)-based body composition assessment, particularly highlighting sarcopenic obesity as a significant predictor of 90-day postoperative complications. However, despite its value in identifying patients at higher risk for complications, CT body composition assessment did not demonstrate a significant impact on survival in this study.

Keywords: radical cystectomy; body composition; outcomes radical; obesity; sarcopenic obesity

Journal Title: Cancers
Year Published: 2025

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