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Chiral α-hydroxyamide L5 derived from (S)-(+)-mandelic acid catalyzes the enantioselective addition of dimethylzinc to isatins affording the corresponding chiral 3-hydroxy-3-methyl-2-oxindoles with good yields and er up to 90:10. Furthermore, several… Click to show full abstract
Chiral α-hydroxyamide L5 derived from (S)-(+)-mandelic acid catalyzes the enantioselective addition of dimethylzinc to isatins affording the corresponding chiral 3-hydroxy-3-methyl-2-oxindoles with good yields and er up to 90:10. Furthermore, several chemical transformations were performed with the 3-hydroxy-2-oxindoles obtained.
Keywords:
catalytic enantioselective;
addition;
enantioselective addition;
me2zn isatins;
addition me2zn
Journal Title: Catalysts
Year Published: 2017
Link to full text (if available)
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Journal Title: Catalysts
Year Published: 2017
Link to full text (if available)
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recommendations!