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Craniofacial Development Is Fine-Tuned by Sox2

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The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision… Click to show full abstract

The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.

Keywords: development; fine tuned; development fine; craniofacial development; tuned sox2

Journal Title: Genes
Year Published: 2023

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