LAUSR

(1) Background: Human settlements are a basic requirement for human survival and development. The natural suitability of human settlements directly affects human health and their quality of life and, to some extent, also dictates the size of the regional population and economy, as well as the level of urbanization. (2) Methods: This study presents a kilometer grid-based comprehensive human settlement suitability (HSS) evaluation model (containing the relief degree of the land surface (RDLS), the temperature–humidity index (THI), the land surface water abundance index (LSWAI), and the land cover index (LCI)). (3) Results: Based on the correlations between the four factors (i.e., the normalized RDLS (NRDLS), normalized THI (NTHI), LSWAI, and LCI), the NRDLS and NTHI were determined to be the leading factors, and the LSWAI and LCI were considered to be the auxiliary factors. The auxiliary factors were used to enhance the comprehensive HSS model determined by the leading factors. Based on this logic, spatial and index models were established separately. The HSS index for the BRI regions ranged from 0.07 to 1.00. Six levels of HSS were determined—namely, unsuitable, critically unsuitable, critically suitable, generally suitable, moderately suitable, and highly suitable conditions. In particular, the human settlements suitability is dominated by critically suitable and suitable conditions that accounted for 63% of the BRI. (4) Conclusions: The evaluation results of human settlements showed that topographic and climatic conditions are important limiting factors for the suitability of human settlements. Due to the renewability and manmade adjustability of hydrological and land cover conditions, the comprehensive suitability of human settlements shows differences in different geographic spaces along the BRI. The results provide a decision-making basis for the research on the resource carrying capacity and reasonable distribution of populations in the BRI, so as to realize the sustainable development along the regions.