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Structure, Function and Regulation of the Plasma Membrane Calcium Pump in Health and Disease

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In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of… Click to show full abstract

In this review, I summarize the present knowledge of the structural and functional properties of the mammalian plasma membrane calcium pump (PMCA). It is outlined how the cellular expression of the different spliced isoforms of the four genes are regulated under normal and pathological conditions.

Keywords: plasma membrane; calcium pump; membrane calcium

Journal Title: International Journal of Molecular Sciences
Year Published: 2022

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