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The Change in Paradigm for NSCLC Patients with EML4–ALK Translocation

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The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is… Click to show full abstract

The severe prognosis linked with a lung cancer diagnosis has changed with the discovery of oncogenic molecularly driven subgroups and the use of tailored treatment. ALK-translocated advanced lung cancer is the most interesting model, having achieved the longest overall survival. Here, we report the most important paradigmatic shifts in the prognosis and treatment for this subgroup population occurred among lung cancer.

Keywords: lung cancer; nsclc patients; patients eml4; change paradigm; eml4 alk; paradigm nsclc

Journal Title: International Journal of Molecular Sciences
Year Published: 2022

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