LAUSR

Simple Summary A key tool in the fight against mosquitoes, which transmit malaria, is the application of insecticidal indoor residual spray (IRS) to the internal walls of buildings where mosquitoes alight and rest to digest their blood-meals. When evaluating the effectiveness of IRS formulations for killing mosquitoes when applied to a wall, it is important that the insecticide is applied evenly at the target dose. Traditionally, IRS is applied using a hand-held pump, but this study showed that an automated track sprayer delivered the desired dose to wall surfaces more accurately and more evenly. This was first shown using a fluorescent tracer to measure spray deposit on the wall of a laboratory, and then by spraying different IRS formulations onto the walls of an experimental hut. Abstract Indoor residual spraying (IRS) has changed little since its introduction in the 1940s. Manual spraying is still prone to variation in insecticide dose. To improve the application of IRS in experimental hut trials, an automated track sprayer was developed, which regulates the speed of application and the distance of the nozzle from the wall, two key sources of variation. The automated track sprayer was compared to manual spraying, firstly using fluorescein solution in controlled indoor settings, and secondly in experimental huts in Tanzania using several IRS products. Manual spraying produced greater variation with both fluorescein and insecticide applications. Both manual and automated spray methods under-dosed the actual dose sprayed compared to the target dose. Overall, the track sprayer treats surfaces more consistently, offering a potential improvement over manual spraying for experimental hut evaluation of new IRS formulations.