Simple Summary G protein-coupled receptors (GPCRs) are responsible for the activity of neuropeptides, and interestingly, a number of GPCRs are well-known as pharmaceutical targets, and some are currently being considered… Click to show full abstract
Simple Summary G protein-coupled receptors (GPCRs) are responsible for the activity of neuropeptides, and interestingly, a number of GPCRs are well-known as pharmaceutical targets, and some are currently being considered as potential pest insect control targets. The purpose of this study is to investigate the function of CCHamide-1 (abbreviated as CCHa1) and its receptor CCHamide1-receptor (abbreviated as CCHa1R), which belongs to the GPCR superfamily in pea aphid, Acyrthosiphon pisum. The pea aphid is a serious agricultural pest and serves as a biological model for various studies. The silencing of CCHa1 significantly reduced the aphid feeding behavior and reproduction, but not its survival.
Journal Title: Insects
Year Published: 2024
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