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Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review

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The high prevalence of obesity and of its associated diseases is a major problem worldwide. Genetic predisposition and the influence of environmental factors contribute to the development of obesity. Changes… Click to show full abstract

The high prevalence of obesity and of its associated diseases is a major problem worldwide. Genetic predisposition and the influence of environmental factors contribute to the development of obesity. Changes in the structure and functional activity of genes encoding adipocytokines are involved in the predisposition to weight gain and obesity. In this review, variants in genes associated with adipocyte function are examined, as are variants in genes associated with metabolic aberrations and the accompanying disorders in visceral obesity.

Keywords: obesity review; genes associated; obesity; variants genes; functionally significant

Journal Title: Journal of Personalized Medicine
Year Published: 2023

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