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Lysine-specific methyltransferase 7 (KMT7) SET7/9, aka Set7, Set9, or SetD7, or KMT5 was discovered 20 years ago, yet its biological role remains rather enigmatic. In this review, we analyze the… Click to show full abstract
Lysine-specific methyltransferase 7 (KMT7) SET7/9, aka Set7, Set9, or SetD7, or KMT5 was discovered 20 years ago, yet its biological role remains rather enigmatic. In this review, we analyze the particularities of SET7/9 enzymatic activity and substrate specificity with respect to its biological importance, mostly focusing on its two well-characterized biological functions: cellular proliferation and stress response.
Keywords:
set7;
stress response;
methyltransferase;
proliferation;
role
Journal Title: Life
Year Published: 2022
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Journal Title: Life
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!