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Trichodermanins C–E (1–3), new diterpenes with a rare fused 6-5-6-6 ring system, have been isolated from a fungus Trichoderma harzianum OUPS-111D-4 separated from a piece of a marine sponge Halichondria… Click to show full abstract
Trichodermanins C–E (1–3), new diterpenes with a rare fused 6-5-6-6 ring system, have been isolated from a fungus Trichoderma harzianum OUPS-111D-4 separated from a piece of a marine sponge Halichondria okadai, and these chemical structures have been established by spectroscopic analyses using IR, MASS, HRFABMS, and NMR spectra. We established their absolute stereostructures by application of the modified Mosher’s method. In addition, 1 inhibited the growth of cancer cell lines potently.
Keywords:
fused ring;
new diterpenes;
marine sponge;
ring system;
trichodermanins new
Journal Title: Marine Drugs
Year Published: 2017
Link to full text (if available)
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Journal Title: Marine Drugs
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!