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The composition of the culture medium has great influence on the metabolite production of the marine fungus Pseudallescheria boydii F44-1. By adding amino acids to GPY culture medium, two new… Click to show full abstract
The composition of the culture medium has great influence on the metabolite production of the marine fungus Pseudallescheria boydii F44-1. By adding amino acids to GPY culture medium, two new bisindole alkaloids, pseudboindoles A and B (1 and 2), together with 11 known indole alkaloids were isolated from the culture broth. Their structures were elucidated by comprehensive analysis of the NMR, MS, IR, and UV spectra. The 3,3′-cyclohexylidenebis(1H-indole) (3) showed cytotoxic activity against various cancer cell lines.
Keywords:
boydii f44;
indole alkaloids;
fungus pseudallescheria;
pseudallescheria boydii;
marine fungus
Journal Title: Marine Drugs
Year Published: 2019
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Journal Title: Marine Drugs
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!