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Stable Tetrodotoxin Production by Bacillus sp. Strain 1839

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For the first time, tetrodotoxin (TTX) was detected in a bacterial strain after five years of cultivation in laboratory conditions since its isolation from the animal host. A reliable method… Click to show full abstract

For the first time, tetrodotoxin (TTX) was detected in a bacterial strain after five years of cultivation in laboratory conditions since its isolation from the animal host. A reliable method suitable for bacterial samples, high-performance liquid chromatography with tandem mass spectrometry, was used for toxin detection in spore and vegetative cultures of Bacillus sp. 1839. TTX was detected in a spore culture of the strain.

Keywords: tetrodotoxin production; bacillus strain; production bacillus; tetrodotoxin; stable tetrodotoxin; strain

Journal Title: Marine Drugs
Year Published: 2019

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