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Highly functionalized furans are the key scaffolds of many pharmaceuticals and bioactive natural products. Herein, we disclose a new fruitful synthesis of polyfunctionalized furans starting from β-nitroenones and α-functionalized ketones.… Click to show full abstract
Highly functionalized furans are the key scaffolds of many pharmaceuticals and bioactive natural products. Herein, we disclose a new fruitful synthesis of polyfunctionalized furans starting from β-nitroenones and α-functionalized ketones. The protocol involves two steps promoted by solid supported species, and it provides the title targets from satisfactory to very good overall yields and in an excellent diastereomeric ratios.
Keywords:
starting nitroenones;
synthesis polyfunctionalized;
new valuable;
furans starting;
polyfunctionalized furans
Journal Title: Molecules
Year Published: 2019
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Journal Title: Molecules
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!