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A concise and scalable synthetic route for optically pure (4S) and (4R)-5-(3′,4′-dihydroxyphenyl)-γ-valerolactones (DHPVs), catechin metabolites, has been developed via the efficient construction of a γ-valerolactone moiety from hexenol. Noticeably, the… Click to show full abstract
A concise and scalable synthetic route for optically pure (4S) and (4R)-5-(3′,4′-dihydroxyphenyl)-γ-valerolactones (DHPVs), catechin metabolites, has been developed via the efficient construction of a γ-valerolactone moiety from hexenol. Noticeably, the different skin wrinkle-reducing activities of each metabolite were revealed via our unique syntheses of DHPVs in an enantiomerically pure form.
Keywords:
wrinkle reducing;
skin wrinkle;
catechin metabolites;
dihydroxyphenyl valerolactones;
reducing activities;
optically pure
Journal Title: Molecules
Year Published: 2020
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Journal Title: Molecules
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!