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Newly synthesized naphthalene diimide carrying two β-cyclodextrins (NDI-β-CyDs) showed improved specificity for the parallel G-quadruplex structure alongside the hybrid G-quadruplex structure. Specifically, the highest binding affinity of NDI-β-CyDs for the… Click to show full abstract
Newly synthesized naphthalene diimide carrying two β-cyclodextrins (NDI-β-CyDs) showed improved specificity for the parallel G-quadruplex structure alongside the hybrid G-quadruplex structure. Specifically, the highest binding affinity of NDI-β-CyDs for the telomere RNA G-quadruplex was observed. The binding simulation indicated that β-cyclodextrins might be available for loop nucleobase inclusion under its complex.
Keywords:
two cyclodextrins;
telomere rna;
naphthalene diimides;
rna quadruplex;
diimides carrying;
carrying two
Journal Title: Molecules
Year Published: 2022
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Journal Title: Molecules
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!