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Copper-Catalyzed Difluoroalkylation Reaction

This review describes recent advances in copper-catalyzed difluoroalkylation reactions. The RCF2 radical is generally proposed in the mechanism of these reactions. At present, various types of copper-catalyzed difluoroalkylation reactions have… Click to show full abstract

This review describes recent advances in copper-catalyzed difluoroalkylation reactions. The RCF2 radical is generally proposed in the mechanism of these reactions. At present, various types of copper-catalyzed difluoroalkylation reactions have been realized. According to their characteristics, we classify these difluoroalkylation reactions into three types.

Keywords: catalyzed difluoroalkylation; difluoroalkylation; copper catalyzed; difluoroalkylation reactions; difluoroalkylation reaction

Journal Title: Molecules
Year Published: 2022

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