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Engineering the Interface between Inorganic Nanoparticles and Biological Systems through Ligand Design

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Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review,… Click to show full abstract

Nanoparticles (NPs) provide multipurpose platforms for a wide range of biological applications. These applications are enabled through molecular design of surface coverages, modulating NP interactions with biosystems. In this review, we highlight approaches to functionalize nanoparticles with “small” organic ligands (Mw < 1000), providing insight into how organic synthesis can be used to engineer NPs for nanobiology and nanomedicine.

Keywords: inorganic nanoparticles; biological systems; nanoparticles biological; interface inorganic; engineering interface; design

Journal Title: Nanomaterials
Year Published: 2021

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