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Ciprofloxacin-Collagen-Based Materials with Potential Oral Surgical Applications

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We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The… Click to show full abstract

We report in this paper the synthesis and characterization of a new collagen-based material. This material was obtained in a spongy form and was functionalized with an antibiotic, ciprofloxacin. The targeted applications of these kind of materials concern the post-operative prophylaxis. The in vitro tests (antimicrobial, cytotoxic, drug release) showed that sponges with a concentration of 0.75 g of ciprofloxacin per gram of collagen could be beneficial for the desired applications.

Keywords: collagen; ciprofloxacin collagen; materials potential; collagen based; potential oral; based materials

Journal Title: Polymers
Year Published: 2020

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