LAUSR

Abstract Introduction : Human papillomavirus infections are the most prevalent sexually transmitted disease among women worldwide. Cervical cancer is the second most frequent disease worldwide in terms of incidence and mortality, and it is primarily responsible for fatalities in low- to middle-income nations, including Ethiopia. In the Hadiya Zone of Southern Ethiopia, the goal of this study is to determine parental knowledge about, acceptance of, and factors related to the human papillomavirus vaccine. Methods : From November to December 2021, a community-based cross-sectional study would be conducted in Hadiya Zone among parents with daughters in the Zone. The study respondents would be chosen using a two-stage sampling technique from parents with a 9-14-year-old daughter. An interviewer-administered questionnaire would be used to collect data. For analysis, the data were entered into Epidata version 3.1 and exported to SPSS version 25. Variables with a p-value less than 0.25 in the bivariate analysis were transferred to multivariate analysis. A logistic regression model was applied to forecast the association between the predictor and outcome variables. Statistical significance was considered at a 0.05 p-value. Results : The study showed that the overall acceptance of parents to vaccinate their daughter with HPV vaccination was 450 (84.9%). Parents of daughters having of male sex (AOR: 0.407; 95%CI: 0.221,0.748), having number of daughters one(AOR: 2.122; 95%CI: 1.221,3.685), government school type(AOR: 0.476;95%CI: 0.263,0.861), poor knowledge(AOR: 0.532;95%CI: 0.293,0.969) and negative attitude(AOR: 0.540;95%CI: 0.299,0.977) were discovered to have a strong correlation. Conclusion : This study found that there was a high level of parental acceptance; attitudes and knowledge about the HPV vaccine are significant in determining their intentions to vaccinate their daughter. Authorities in areas where cervical cancer incidence is at risk should plan and implement by providing health information regarding the human papillomavirus vaccination with an emphasis on raising community awareness.