LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Analysis of the Prevalence of Canine Splenic Mass Lesions in Republic of Korea via Histopathological Diagnosis with Immunohistochemistry

Photo by impulsq from unsplash

Simple Summary The histopathological diagnosis of canine splenic mass lesions is crucial for determining prognosis. Herein, we analyzed the prevalence of canine splenic mass lesions in Republic of Korea via… Click to show full abstract

Simple Summary The histopathological diagnosis of canine splenic mass lesions is crucial for determining prognosis. Herein, we analyzed the prevalence of canine splenic mass lesions in Republic of Korea via histopathological diagnosis. Immunohistochemistry was performed for specific tumor markers for a more accurate diagnosis. The results of this study will aid veterinary clinicians in communication with pet owners about prognoses and recommendations for splenectomy. This study will facilitate additional investigations with more detailed comparisons of splenic mass lesions between small- and large-breed dogs. Abstract The histopathological diagnosis of canine splenic mass lesions is crucial for prognostication. However, thus far, no study has been conducted on the histopathology of canine splenic mass lesions in Republic of Korea. Herein, the prevalence of splenic diseases was analyzed in 137 canine splenic mass lesions via histopathological diagnosis, and the microscopic pattern associated with each disorder was described. Immunohistochemistry was performed for CD31, CD3, PAX5, Iba1, and C-kit for a more accurate diagnosis of splenic tumors. The proportion of non-neoplastic disorders, including nodular hyperplasia (48.2%, n = 66) and hematoma (24.1%, n = 33), was 72.3%. Splenic tumors, including splenic hemangiosarcoma (10.2%, n = 14), splenic lymphoma (nodular and diffuse types, 8.0%, n = 11), splenic stromal sarcoma (7.3%, n = 10), myelolipoma (1.5%, n = 2), and mast cell tumors (0.7%, n = 1), accounted for 27.7% of cases. The results of this study will aid veterinary clinicians in communication with pet owners about prognoses, recommendations for splenectomy, and subsequent histopathological diagnoses. This study will facilitate further investigations with more detailed comparisons of splenic mass lesions between small- and large-breed dogs.

Keywords: splenic mass; canine splenic; diagnosis; mass lesions

Journal Title: Veterinary Sciences
Year Published: 2023

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.