LAUSR

Simple Summary This report explores the challenges of translating new therapeutic drugs from preclinical studies to human clinical trials, with a focus on the limitations of using traditional laboratory animals like mice and rats. Despite their widespread use in disease research, these animals often fail to accurately predict human outcomes, leading to a high failure rate in clinical trials. To bridge this gap, we discuss the potential of using companion animals that naturally develop chronic conditions similar to humans, such as dogs and cats, as more relevant models for human diseases. The report also underscores the significance of enhancing collaboration between veterinarians and doctors to address potential communication challenges and fully leverage the potential of companion animals in research. By fostering this interdisciplinary approach, we can improve the success rate of clinical trials and advance healthcare for both humans and animals.