LAUSR

Relevance . It is difficult to distinguish between healthy gums and chronic gingivitis, so the study of the effect of individual bacteria on the development of chronic gingivitis is an important step towards understanding the role of microbiota in the pathogenesis of the disease. Purpose . To investigate the genomic composition of microbiol dentogingival sulcus in young people with chronic gingivitis – a healthy living on the territory of Kazan of Republic Tatarstan. Materials and methods . The study included 13 young people (6 boys and 7 girls) with chronic gingivitis. The control group consisted of 11 donors (6 boys and 5 girls) without inflammatory periodontal disease. All participants of the study were conditionally healthy, aged 18-19 years. Results . This paper describes a universal algorithm of metagenomic studies and the results of clinical and microbiological studies of the microbiome of the dentogingival sulcus in patients without orthodontic and mucogingival pathology with a real understanding of its composition and the definition of both known and previously undefined uncultivated phylotypes. Conclusion. Unique microbial communities not found in previously studied metagenomes were found in a sample of metagenomic samples.