LAUSR

. ABSTRACT Background: Self-reported functional capacity measures have an uncertain role in the pre-operative cardiovascular risk stratification. Aim: The aim of this substudy was to evaluate whether self-reported metabolic equivalent (MET) could improve the prediction of postoperative myocardial injury over other well-established cardiovascular risk factors. Methods: This is a post hoc analysis of an international multicentre prospective cohort study. We recruited patients ≥45 years old having elective, elevated -risk noncardiac surgery in 45 centres across 17 countries between June 2017 and April 2020. The primary outcome was myocardial injury defined according to the Fourth Universal Definition of Myocardial Infarction. We measured the fraction of new prognostic information added by self-reported MET using multivariable logistic regression. Results: 860 (41.3%) patients suffered a myocardial injury. In patients without systematic troponin surveillance the odds ratio for myocardial injury with each 1-point increment in MET equalled 1.03 (95% confidence interval [CI], 0.99–1.07). The new prognostic information,