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wFLFM: enhancing the resolution of Fourier light-field microscopy using a hybrid wide-field image

We introduce wFLFM, an approach that enhances the resolution of Fourier light-field microscopy (FLFM) through a hybrid wide-field image. The system exploits the intrinsic compatibility of image formation between the… Click to show full abstract

We introduce wFLFM, an approach that enhances the resolution of Fourier light-field microscopy (FLFM) through a hybrid wide-field image. The system exploits the intrinsic compatibility of image formation between the on-axis FLFM elemental image and the wide-field image, allowing for minimal instrumental and computational complexity. The numerical and experimental results of wFLFM present a two- to three-fold improvement in the lateral resolution without compromising the 3D imaging capability in comparison with conventional FLFM.

Keywords: resolution; microscopy; field; field image; wide field

Journal Title: Applied physics express
Year Published: 2021

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