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New sugar hydrazones linked to chroman ring system and their derived oxadiazole acyclic nucleoside analogs were synthesized from the substituted ethyl ester oxime derivative. The 2-sustituted 1,3,4-oxadiazole5-thione prepared from acid… Click to show full abstract
New sugar hydrazones linked to chroman ring system and their derived oxadiazole acyclic nucleoside analogs were synthesized from the substituted ethyl ester oxime derivative. The 2-sustituted 1,3,4-oxadiazole5-thione prepared from acid hydrazide was glycosylated to afford the corresponding thioglycosides, not the N-linked glycosides. The novel compounds were evaluated for their antimicrobial activity and showed different degrees of activities.
Keywords:
new oxadiazole;
thioglycoside analogs;
preparation new;
oxadiazole acyclic;
nucleoside thioglycoside;
acyclic nucleoside
Journal Title: Revista De Chimie
Year Published: 2017
Link to full text (if available)
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Journal Title: Revista De Chimie
Year Published: 2017
Link to full text (if available)
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recommendations!