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CRISTINA BICA1, MIHAELA CHINCESAN2*, DANIELA ESIAN1, KRISZTINA MARTHA4, VALENTIN ION5, LARISA ANDREEA MARINESCU4, KAMEL EARAR6, MADALINA NICOLETA MATEI6 1University of Medicine and Pharmacy of Tirgu Mures, Faculty of Dentistry, Department of Paediatric Dentistry, 38 Gh. Marinescu Str., 540139, Targu Mures, Romania 2University of Medicine and Pharmacy of Tirgu Mures, Faculty of Medicine, Department of Paediatric Oncology, 38 Gh. Marinescu Str., 540139, Targu Mures, Romania 3Mures County Emergency Hospital, 50 Gh. Marinescu Str., 540136, Targu Mures, Romania 4University of Medicine and Pharmacy of Tirgu Mures, Department of Fixed Prosthodontics, 38 Gh. Marinescu Str., 540139, Targu Mures, Romania 5University of Medicine and Pharmacy of Tirgu Mures, Faculty of Pharmacy, Department of Analytical Chemistry and Medicine Analysis, 38 Gh. Marinescu Str., 540139, Targu Mures, Romania 6Dunarea de Jos University of Galati, Medicine and Pharmacy Faculty, Departament of Dentistry, 47 Domneasca Str., 800008, Galati, Romania.