LAUSR

The s study was carried out in Kirkuk city, from 20th January to September to November 2019 included40 Diabetic patients with retinopathy and 40 healthy persons within the range of age: 45-75 years ofold. The information about patients in this study was retrieved from patient’s itself. The diabetic patientswith retinopathy were diagnosed by analysis RBS and HbA1c and fundoscopical examination by theophthalmologist. The criteria of exclusion include non-diabetic and malignant disease. The results of thepatients groups were compared with healthy individuals nearly comparable age and BMI. Four ml of bloodwere collected from patients and for determination of irisin, vaspin and HbA1c. The study showed that themean serum level of irisin was significantly elevated in DR patients compared to control group (27.57 ±4.22 and 17.57 ± 5.9 pg/ml) respectively at a P value < 0.01.This study showed that the mean serum levelvaspin was higher in DR patients especially in persons with high BMI and decreased in lower BMI persons(75.1, 59.3 and 48.3 ng/ml)respectively but still higher than healthy ones (P<0.01), as compared with thecontrol group (32.17ng/ml). The study showed that, HbA1c was elevated significantly (P<0.01) in diabeticretinopathy patients (10.17%) compared with healthy control (5.17%),. The study concluded that, vaspinand irisin levels were highly elevate din diabetic patients with retinopathy