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Comparison of Average Inhibition Zones of Methanolic Extracts of Chaetomium globosum on the Growth of Different Groups of Pathogenic Micro-Organisms

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The objectives of this study were analysis of the secondary metabolite products and evaluation of antibacterial activity. The FTIR analysis of Chaetomium globosum proved the presence of functional groupassignment Alkyl… Click to show full abstract

The objectives of this study were analysis of the secondary metabolite products and evaluation of antibacterial activity. The FTIR analysis of Chaetomium globosum proved the presence of functional groupassignment Alkyl halides, Amide, and Alkane with Peak (Wave number cm-?) 1018.41 (Strong), 1238.30(Strong), 1317.38 (Strong), 1379.10 (Strong), 1614.42 (Bending), 2850.79 (Strong), 2920.23 (Strong). Zoneof inhibition (mm) of test bacterial strains to Chaetomium globosum bioactive compounds and standardantibiotics were (4.00±0.31), (4.77±0.13), (5.00±0.16), (3.22±0.41), and (4.29±0.11) uses Chaetomiumglobosum bioactive compounds, and (2.01±0.10), (1.77±0.41), (1.98±0.11), (2.00±0.30), and (1.05±0.42)uses Rifambin, and (2.42±0.18), (2.12±0.46), (1.40±0.12), (1.00±0.10), and (2.90±0.47) uses Kanamycinfor Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Klebsiella pneumonia, Pseudomonaseurogenosa respectively. Chaetomium globosum was very highly active against Escherichia coli (4.77±0.13).

Keywords: inhibition zones; comparison average; chaetomium globosum; average inhibition; inhibition; zones methanolic

Journal Title: Medico-Legal Update
Year Published: 2020

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