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[Genomic structure of varicella-zoster virus and its vaccine application status].

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With the determination of the whole genome sequence of varicella-zoster virus (VZV) virus, the successful breakthrough of infectious cloning technology of VZV, and the emergence of effective preventive vaccines, which… Click to show full abstract

With the determination of the whole genome sequence of varicella-zoster virus (VZV) virus, the successful breakthrough of infectious cloning technology of VZV, and the emergence of effective preventive vaccines, which have been proven to be effective and safe, varicella has become a disease preventable by specific immunity. This article will review the genomic structure, epidemiological characteristics, and research application progress of varicella vaccine and herpes zoster vaccine of varicella zoster virus to provide reference for primary prevention of the disease.

Keywords: zoster virus; genomic structure; varicella zoster; virus; varicella

Journal Title: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]
Year Published: 2023

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