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Tissue-engineering airway reconstruction is a tracheal replacement therapy, which uses different materials, such as primary, allogeneic or synthetic, combined with seed cells and growth factors to repair the defect airway… Click to show full abstract
Tissue-engineering airway reconstruction is a tracheal replacement therapy, which uses different materials, such as primary, allogeneic or synthetic, combined with seed cells and growth factors to repair the defect airway and restore its physiological function. The choice of stent graft is the key to the success or failure of airway reconstruction. By improving the performance of graft scaffolds, it has similar mechanical properties and biocompatibility with natural gas tubes, promoting vascularization and re-epithelization, reducing immunogenicity and completing airway reconstruction. This article aims to review advances in the study of graft scaffolds for airway remodeling. Key words: Trachea; Stents; Regenerative medicine; Tissue engineering
Journal Title: International Journal of Surgery
Year Published: 2018
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