LAUSR

Objective To evaluate the efficacy and clinical outcomes of early laparoscopic radiofrequency ablation(RFA) forspontaneously ruptured hepatocellular carcinoma (HCC). Methods A retrospective analysis was conducted on 12 patients with spontaneously ruptured HCC treated by laparoscopic RFA from April 2005 to June 2018 in the West Campus of Beijing Chao-yang Hospital, Capital Medical University. The successful rate, safety, peritoneal recurrence rate, complete ablation rate and survival rate of RFA were respectively analyzed. Results The median size of the 12 HCC cases was 5.85 cm (4.0-10.1 cm) in the maximal dimension. Procedures of laparoscopic RFA ablation were performed successfully for all patients. Complete ablation was achieved in 58.3%patients (7/12). Five patients with incompletely ablated tumors received repeated RF ablation to achieve completeablation. Four patients (33.3%) developed minor complications(Dindo-Clavien gradeⅠ). The mean follow-up of 36.8 months, 4 patients (33.3%) were alive and 8 (66.7%) died. Of the 12 patients, the 1- and 3-year survival rates were 90.0% and 60.0%, respectively.No patient had peritoneal recurrence. Conclusion Early laparoscopic RFA therapy is an minimally invasive, safety and effective treatment measure for spontaneouslyruptured HCC in selected patients, which presents an advantage of achieving simultaneous hemostasis, tumorelimination, and rinsing of peritoneal cavity to minimize the risk of peritoneal metastasis. Key words: Carcinoma, hepatocellular; Laparoscopes; Hemorrhage; Radiofrequency ablation