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The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times… Click to show full abstract
The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving similar or higher yields. In addition, the use of inorganic bases was demonstrated to increase the reaction yield under batch conditions.
Keywords:
heteroarenes continuous;
trifluoromethoxylation arenes;
photocatalytic trifluoromethoxylation;
continuous flow;
arenes heteroarenes
Journal Title: Beilstein Journal of Organic Chemistry
Year Published: 2020
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Journal Title: Beilstein Journal of Organic Chemistry
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!