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Synthetic study toward the diterpenoid aberrarone

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An approach to aberrarone, an antimalarial diterpenoid natural product with tetracyclic skeleton is reported. Key to the stereoselective preparation of the 6-5-5 tricyclic skeleton includes the mediation of Nagata reagent… Click to show full abstract

An approach to aberrarone, an antimalarial diterpenoid natural product with tetracyclic skeleton is reported. Key to the stereoselective preparation of the 6-5-5 tricyclic skeleton includes the mediation of Nagata reagent for constructing the C1 all-carbon quaternary centers and gold-catalyzed cyclopentenone synthesis through C–H insertion.

Keywords: study toward; synthetic study; diterpenoid aberrarone; chemistry; aberrarone; toward diterpenoid

Journal Title: Beilstein Journal of Organic Chemistry
Year Published: 2022

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