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Synthetic study toward vibralactone

A synthetic study toward vibralactone, a potent inhibitor of pancreatic lipase, is reported. The synthesis of the challenging all-carbon quaternary center within the cyclopentene ring was achieved through intramolecular alkylidene… Click to show full abstract

A synthetic study toward vibralactone, a potent inhibitor of pancreatic lipase, is reported. The synthesis of the challenging all-carbon quaternary center within the cyclopentene ring was achieved through intramolecular alkylidene carbene C–H insertion.

Keywords: study toward; chemistry; toward vibralactone; synthetic study

Journal Title: Beilstein Journal of Organic Chemistry
Year Published: 2025

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