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Contralateral Suppression at Adrenal Venous Sampling Is Associated with Renal Impairment Following Adrenalectomy for Unilateral Primary Aldosteronism (Endocrinol Metab 2021;36:875-84, Ye Seul Yang et al.)

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We thank Tan et al. for their interest in our study and for their effort to elaborate on the association between age and chronic kidney disease (CKD) after adrenalectomy in… Click to show full abstract

We thank Tan et al. for their interest in our study and for their effort to elaborate on the association between age and chronic kidney disease (CKD) after adrenalectomy in patients with primary aldosteronism (PA). We demonstrated that a contralateral suppression index (CSI) ≤ 0.26 at adrenal venous sampling was associated with incident CKD, especially in patients > 50 years of age, after adrenalectomy [1]. We determined the cut-off age for this study by performing a receiver operating characteristic curve analysis. We agree with their interest in differences between elderly patients and nonelderly patients regarding renal outcomes after adrenalectomy. In our study population, the prevalence of postoperative CKD, which was defined as a postoperative estimated glomerular filtration rate (GFR) less than 60 mL/min/1.73 m 2 in

Keywords: sampling associated; adrenal venous; contralateral suppression; primary aldosteronism; venous sampling

Journal Title: Endocrinology and Metabolism
Year Published: 2022

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