Photo from academic.microsoft.com
Living organisms have evolved ubiquitous mechanisms to manage a vast multitude of stressors and noxious conditions. Although Nrf2 mainly plays a major role in cellular antioxidant defense, results from recent… Click to show full abstract
Living organisms have evolved ubiquitous mechanisms to manage a vast multitude of stressors and noxious conditions. Although Nrf2 mainly plays a major role in cellular antioxidant defense, results from recent studies have highlighted its ubiquitous roles in cellular cytoprotection including anti-inflammatory function. As oxidative stress and inflammatory tissue damage are two major culprits in the pathogenesis of the majority of malignancies and other disorders, Nrf2 is recognized as a potential preventive target. Some chemoprotective and chemopreventive phytochemicals are capable of activating Nrf2 signaling, thereby fortifying cellular defense capacity.
Journal Title: Journal of Food and Drug Analysis
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!